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Ticarcillin+clavulanic Acid

About Ticarcillin+clavulanic Acid

Clavulanic Acid+ticarcillin is an antibiotic medicine used to treat bacterial infections of the skin, throat, ear, nose, teeth, gastrointestinal tract, and lungs. It is also used to treat urinary tract, gynaecological and genital infections. A bacterial infection occurs when harmful bacteria enter and grow in the body and multiply quickly, leading to the infection.

Clavulanic Acid+ticarcillin contains Ticarcillin (carboxypenicillin) and Clavulanic acid. Clavulanic Acid+ticarcillin Binds to one or more penicillin-binding proteins to inhibit the biosynthesis of bacterial cell walls, thereby causing a bactericidal effect.

Clavulanic Acid+ticarcillin may cause side effects such as indigestion, diarrhoea, nausea, vomiting, headache, rashes, and stomach pain. If these side effects persist or worsen, please consult your doctor. Clavulanic Acid+ticarcillin should be taken as advised by your doctor. A trained healthcare professional will administer Clavulanic Acid+ticarcillin. Do not self-administer.

Clavulanic Acid+ticarcillin should be avoided if you are allergic to it or other antibiotics. Let your doctor know your complete medical history and ongoing medications to rule out any side effects/interactions. Inform your doctor if you have liver/kidney problems, bleeding disorders, and hypokalemia before receiving Clavulanic Acid+ticarcillin. Also, let your doctor know if you are pregnant or breastfeeding.

Uses of Ticarcillin+clavulanic Acid

Treatment of Bacterial Infections

Medicinal Benefits

Clavulanic Acid+ticarcillin is a combination medicine containing Ticarcillin (carboxypenicillin) and Clavulanic acid (beta-lactamase enzyme). It is a broad-spectrum antibiotic that acts against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) bacteria. Clavulanic Acid+ticarcillin is used in the treatment of several bacterial infections. Ticarcillin works by inhibiting the formation of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Clavulanic acid inhibits the beta-lactamase enzyme, which prevents bacteria from destroying the efficacy of beta-lactam antibiotics.

Directions for Use

A trained healthcare professional will administer Clavulanic Acid+ticarcillin in a hospital setting. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ticarcillin+clavulanic Acid

  • Nausea
  • Diarrhoea
  • Stomach upset
  • Indigestion
  • Vomiting
  • Headache
  • Rashes
  • Pain at the site of injection
  • Injection site reactions

Drug Warnings

Discontinue the medicine and inform your doctor if you develop any hypersensitivity reactions during the treatment or are known to be allergic to any of its components or other antibiotics. Keep your doctor informed about your health condition, including complete medication history and medical history, to rule out any side effects/interactions. Clavulanic Acid+ticarcillin may cause renal insufficiency, electrolyte imbalance, severe diarrhoea, convulsions, bleeding, and serious anaphylactic reactions. Hence, inform your doctor if you have any history of liver/kidney problems, hypokalemia, fits, or bleeding disorders before taking Clavulanic Acid+ticarcillin. Avoid alcohol consumption during the treatment to prevent unpleasant side effects. Inform your doctor if you are pregnant or breastfeeding.

Drug Interactions

Drug-Drug Interactions: Clavulanic Acid+ticarcillin may interact with the aminoglycosides (gentamicin, neomycin, amikacin), anti-gout medicine (probenicid), oral contraceptives, etc.

Drug-Food Interactions: Avoid alcohol consumption and smoking.  

Drug-Disease Interactions: Inform your doctor if you have kidney problems, liver disease, and bleeding disorders before receiving Clavulanic Acid+ticarcillin.

Drug-Drug Interactions Checker List:

  • AMIKACIN
  • GENTAMICIN
  • NEOMYCIN
  • PROBENECID
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consuming alcohol while on treatment with Clavulanic Acid+ticarcillin, as it may worsen your health condition.

    • Safety Warning

      Pregnancy

      caution

      If you are pregnant or planning pregnancy, inform your doctor before receiving Clavulanic Acid+ticarcillin. Your doctor may prescribe this medicine if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      Avoid taking Clavulanic Acid+ticarcillin if you are breastfeeding, as it may harm your infant. Consult your doctor for more information.

    • Safety Warning

      Driving

      caution

      Avoid driving after taking Clavulanic Acid+ticarcillin as it may cause allergies and dizziness.

    • Safety Warning

      Liver

      caution

      If you have a pre-existing or a history of liver disease, inform your doctor before taking Clavulanic Acid+ticarcillin. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Kidney

      caution

      Kidneys excrete Clavulanic Acid+ticarcillin. Therefore, if you have any history of kidney disease, inform your doctor before receiving Clavulanic Acid+ticarcillin. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Children

      safe if prescribed

      Clavulanic Acid+ticarcillin is safe for use in children above 3 months of age. Your paediatrician will decide the dose of the medicine based on the body weight.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include more fiber-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate growth.
    • Fiber foods may help restore healthy gut bacteria after a course of antibiotics.
    • Avoid taking too much calcium or iron-enriched foods, as it might affect the working of Clavulanic Acid+ticarcillin. 
    • Make sure to drink more fluids to avoid dehydration.
    • Avoid alcohol consumption and smoking for fast recovery.

    Special Advise

    • Clavulanic Acid+ticarcillin should be avoided if you observe serious anaphylactic reactions, and inform your doctor
    • This medicine produces false positive protein reactions and false positive Coombs tests. Hence, inform your lab technician if you undergo any such lab test.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infection: A bacterial infection occurs when harmful bacteria enter, grow, and infect the body. It can infect any part of the body and multiply very quickly. These infections vary from minor illnesses to severe brain infections like meningitis and encephalitis. When you get infected with these germs, you can experience generalized symptoms like fevers, chills, and fatigue. Generally, individuals who have weak immune systems are more prone to infections.

    FAQs

    Clavulanic Acid+ticarcillin is used to treat Bacterial infections.

    Clavulanic Acid+ticarcillin works by inhibiting the formation of the bacterial cell wall, eventually resulting in the death of the bacterial cell.

    No, Clavulanic Acid+ticarcillin is not used to treat viral infections. Clavulanic Acid+ticarcillin is an antibiotic that is used to treat only bacterial infections.

    Yes, it is safe to use Clavulanic Acid+ticarcillin if taken in the dose and duration prescribed by the doctor. However, it may cause side effects like indigestion, diarrhoea, nausea, vomiting, headache, rashes, and stomach pain.

    A trained healthcare professional will administer Clavulanic Acid+ticarcillin intravenously in a hospital setting. Hence, do not self-administer.

    Clavulanic Acid+ticarcillin may cause hypersensitivity reactions, clostridium difficile associated diarrhoea (CDAD), and convulsions on overdose. Hence, inform your doctor if you experience anaphylactic reactions, diarrhoea or convulsions during treatment with Clavulanic Acid+ticarcillin.

    Clavulanic Acid+ticarcillin may affect gut flora which might lower oestrogen reabsorption. This might reduce the effectiveness of birth control pills, increasing the risk of contraceptive failure. Consult the doctor if you are using contraceptives; the doctor may suggest alternate forms of contraception.

    As Clavulanic Acid+ticarcillin is administered by the doctor, it is unlikely to exceed the recommended dose. However, taking more than the prescribed dose of Clavulanic Acid+ticarcillin can increase the risk of side effects like convulsions, especially in the presence of impaired renal function. Consult the doctor if you think there has been an overdose.

    Clavulanic Acid+ticarcillin should be stored in a cool and dry place away from sunlight. Dispose of unused or expired medicine according to local regulations.

    Clavulanic Acid+ticarcillin can cause allergic reactions like skin rash, pruritus, urticaria, arthralgia, myalgia, fever, chills, chest discomfort, anaphylactic reactions, and bullous reactions (including erythema multiforme, toxic epidermal necrolysis, and Stevens-Johnson syndrome). If you experience any of these symptoms while using Clavulanic Acid+ticarcillin consult your doctor immediately.

    Clavulanic Acid+ticarcillin may cause diarrhoea. To cope with diarrhoea, stay hydrated by drinking plenty of water, clear broth, or electrolyte-rich drinks. Rest and follow a bland diet of easy-to-digest foods like bananas, rice, and toast. Avoid triggers like spicy foods, caffeine, and alcohol. However, if diarrhoea persists, consult your doctor immediately.

    The common side effects of Clavulanic Acid+ticarcillin may include indigestion, diarrhoea, nausea, vomiting, headache, rashes, and stomach pain. If these side effects persist or worsen, please consult your doctor.

    Available Medicines for

    Ticarcillin+clavulanic Acid

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